Hair Loss in Men

Male hair loss or Male Pattern Baldness (MPB) also known as Androgenetic Alopecia has been with us since the dawn of time. Many different treatments have been tested over the years, mainly to no effect.

It’s only in the past 20 years that truly effective hair loss treatments have been discovered. The breakthrough came from understanding that a hormone known as Dihydrotesterone (DHT) which all men carry, effects the cells inside the base of the hair root and is the cause of male hair loss.

You need to have a genetic pre-disposition to MPB for this hormone to affect the hair root cells. Once it’s destroyed, no medical treatment can help. That’s why, if you want to regrow your own hair, it’s vital to start our regrowth treatment program as soon as you can.

Evolving methods of treatment

Understanding and management of all things health and medical are, by nature, always evolving. New knowledge, and its practical applications are acquired in small increments. Occasionally, though, a discovery is made of such significance that it becomes a game-changer. Newer understanding obliterates the paradigm that previously shaped our thinking and actions.

Such a fundamental shift, with the creation of a dynamic new paradigm, has emerged in the science of hair regulation and loss.

The Journal of Drugs in Dermatology, in “New Insight into the Pathophysiology of Hair Loss Triggers a Paradigm Shift in the Treatment Approach,” November 2017, updates healthcare providers about these new discoveries and their long-hoped-for benefits.

More than 60 percent of men, and more than 40 percent of women, in their lifetimes, will experience a condition associated with hair loss. it. Our hair is important to our appearance and social exchanges. Hair loss can be devastating, leaving sufferers feeling hopeless. Psychological trauma is common, aggravated by the lack of treatments that are available, effective, comprehensive, and free of noxious side-effects.

Understanding hair loss starts with understanding hair structure and growth.

Distinct Structures of the Hair

Hair has two distinct structures – the follicle, within the skin, and the shaft, the hair seen coming from the scalp.

Hair Follicles

The hair follicle is a tunnel-like segment of the epidermis (the outer layer of skin) that extends down into the dermis (a deeper layer of skin.) The follicle contains several layers that all have separate functions. At the base of the follicle is the papilla, which contains capillaries. These are the tiny blood vessels that nourish the cells. The living part of the hair is the deepest aspect of the follicle surrounding the papilla, called the bulb. Two sheaths, one inner and one outer, surround the follicle. These structures protect and form the growing hair shaft. The inner sheath follows the hair shaft and ends below the opening of a sebaceous (oil) gland, vital because it produces sebum, which conditions the hair and skin.

Hair Shafts

A hair shaft is made in three layers, of a hard protein called keratin. This protein comes from dead cells; the hair that you see is not a living structure. The inner layer of the shaft is the medulla. The second layer is the cortex, and the outer layer is the cuticle. The cortex makes up most of the hair shaft. The cuticle is a tightly formed structure made of overlapping scales, like shingles on a roof. Both the cortex and the medulla hold the hair’s pigment, giving it colour.

Hair Growth Cycle

Hair on the scalp grows about 0.3 to 0.4 mm/day (about 15cm per year.) Hairs will be found in one of the three stages of growth and shedding: anagen, catagen, and telogen, at any given time.


Anagen is the active phase of hair growth. The cells in the root of the hair are dividing rapidly, forming a new hair; it pushes the club hair (a strand leaving the anagen phase of growth) up the follicle and eventually out. Each hair stays in this active phase of growth for two to six years.


The catagen phase is transitional; about 3% of all hairs are in this phase at any time. The phase lasts for two to three weeks. Growth stops, the outer root sheath shrinks, and attaches to the root of the hair, now called a club hair.


Telogen is the resting phase of the hair growth cycle, accounting for 6% to 8% of all hairs. It lasts for about 100 days for hairs on the scalp. Normal, daily, hair loss is 50-100 telogen-phase hairs.

Causes of Hair Loss

There are many causes of hair loss.

From androgen hormones; psychosocial stress, poor nutrition, genetics, autoimmune diseases, metabolic diseases, ultraviolet light, pollution, and on it goes.

Traditionally, dermatologists have considered each case of hair loss as the result of a distinct, single cause, e.g. genetic vs acquired, scarring vs nonscarring, intrinsic vs extrinsic. Such distinctions among hair loss led to the development of drugs that target single mechanisms of loss (e.g. finasteride suppressing dihydro-testosterone DHT.)

New Findings

Newer findings from the considerable research on causes of hair loss have revealed that it is a multifactorial condition, involving many factors and signalling pathways.  To succeed best to avoid single methods of treatment.

A paradigm shift in hair loss treatment is necessary. It is now understood the importance of multi-targeting therapeutic approaches that address not only androgens but also inflammation, oxidative stress, ageing, elevated stress mediators like cortisol, their downstream signalling mediators, and which stimulate a nutrient-rich microenvironment in the hair follicle, to promote repair and structural regeneration.

Restoration of hair growth and density never achieved previously, is now evident in so many cases as a result of multifaceted treatments.

The results with multi-mechanism treatments have far surpassed all expectations of dermatologists and researchers.

Multi-targeted therapies such as low-level laser light and nutraceuticals are emerging and increasingly recognised for their efficacy as either standalone treatments or in combination with traditional hair loss protocols.

Hair Centre International –  Hair Loss Treatment

Hair Centre International clinics are leading the industry in the multi-targeted approach for hair loss treatment.   Treatment protocol includes;

  • Pharmacy supplied prescription lotion, a unique chemist compound solution, developed by Hair Centre International and available only to Hair Centre International clients. To return hair follicles to the growth (anagen) phase, we have formulated the most effective medical stimulant known. We also add retinoids to improve scalp health.
  • Use of a prescription dihydro-testosterone (DHT) inhibitor, important to controlling the androgen-associated aspects of genetic hair loss, and
  • Herbal products which block androgen receptors, also
  • The use of LLLT, either in clinic, or via our laser technology, to decrease inflammation of the hair follicles, and to improve circulation in the scalp, and
  • Cleansing products free of sulphates – to ensure a healthy environment for newly growing hair, and
  • Trained consultants to evaluate lifestyle choices, including nutrition, that may affect hair growth.

These are just the beginning of the many and varied treatments available. To achieve your goals we will design a personal plan of action and selection of products most suited to you.

You probably have some questions or concerns about your own hair. The earlier treatment begins, the better the results. For many people, that first phone call for your free consultation is the toughest. Most wish they had called sooner.